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KITP Conference: Biological Physics of Biomolecular Condensates: Bridging Theory and Experiment
(Jun 16-18, 2025)
Coordinators: Jerelle Joseph, Frank Jülicher, Stephanie Weber, and David Zwicker
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Program Overview
Monday, Jun 16, 2025
Session
Chair: Trevor Grand Pre (Princeton)
8:50am
Lars Bildsten (KITP)
Welcome
[Video]
9:00am
D. Allan Drummond (U. Chicago)
Biology and physics of stress-induced mRNP condensation
[Slides]
[Video][CC]
9:45am
Allie Obermeyer (Columbia)
Metabolic Activity to Animate Coacervate Materials
[Video][CC]
10:30am
Morning Break
11:00am
Simon Alberti (TU Dresden)
Biomolecular condensates in stress responses and disease
[Video][CC]
11:45am
Sam Safran (Weizmann Inst.)
Mesoscale properties of protein clusters determine the nature of liquid-liquid phase separation
[Video][CC]
12:30pm
Lunch Break
Session
Chair: Krishna Shrinivas (Northwestern)
2:00pm
Tanja Mittag (St. Jude)
Emergent properties of condensates and their effects on protein function and disease processes
[Slides]
[Video][CC]
3:30pm
Afternoon Break
POSTER SESSION
5:30pm
SHUTTLE TO BWSCI
Tuesday, Jun 17, 2025
Session
Chair: Antonia Statt (UIUC)
9:00am
Ben Schuler (Zurich)
Probing the dynamics of biomolecular complex coacervates from molecular to mesoscopic scales
[Slides]
[Video][CC]
9:45am
Keren Lasker (Scripps Institute)
Linking Structure and Function in the Pop Condensate
[Video][CC]
10:30am
Morning Break
11:00am
Frank Julicher (MPI-PKS)
Active processes in condensates and droplets
[Video][CC]
11:30am
William Jacobs (Princeton)
An information bottleneck perspective on IDP interaction specificity
[Video][CC]
12:00pm
Steph Weber (McGill U)
Active transcription controls the kinetics of nucleolar assembly in early C. elegans embryos
[Slides]
[Video][CC]
12:30pm
Lunch Break
Session
Chair: Guido Kusters (MPI-DS)
2:00pm
Sebastian Aland (HTW Dresden)
Biomolecular condensates wetting membranes - dynamic insights from numerical simulations
[Slides]
[Video][CC]
2:30pm
Leonor Saiz (UC Davis)
Disassembly of Hardened Condensates: Hsp70-Mediated Unbundling of α-Synuclein Fibrils
[Embargoed]
3:00pm
Jeremy Schmit (Kansas St.)
Structure/function and emergent concepts at the condensate scale
[Slides]
[Video][CC]
3:30pm
Afternoon Break
4:00pm
Dani Cai (Johns Hopkins)
Uncovering the Interactome of Membrane-less Organelles
[Video][CC]
4:30pm
Kurt Kremer (MPI-P)
Intrinsic stiffness and Theta solvent regime of model amino acid chains: Implications for liquid liquid phase separation
[Slides]
[Video][CC]
5:00pm
Chris Weber (U Augsburg)
Theory of surface phase separation of membrane-binding proteins
[Video][CC]
5:30pm
RECEPTION
6:00pm
SPECIAL EVENTS DINNER
7:30pm
SHUTTLE TO BWSCI
Wednesday, Jun 18, 2025
Session
Chair: Dilimulati Aierken (Princeton)
9:00am
Tuomas Knowles (Cambridge)
Role of condensates in protein aggregation
[Video][CC]
9:45am
Agnes Toth Petroczy (MPI-CBG)
Biomolecular condensates across the Tree of life
[Video][CC]
10:30am
Morning Break
11:00am
Lindsay Case (MIT)
Understanding the role of membranes in regulating condensates
[Video][CC]
11:30am
Hue Sun Chan (U Toronto)
Field-theoretic approaches to physical principles in sequence-dependent phase separation of disordered heteropolymers
[Slides]
[Video][CC]
12:00pm
Jerelle Joseph (Princeton)
Prediction of small-molecule partitioning into biomolecular condensates from simulation
[Video][CC]
12:30pm
Lunch Break
Session
Chair: Kathrin Laxhuber (MPI-PKS)
2:00pm
Ned Wingreen (Princeton)
If you're not in, you're out: conformational entropy of intrinsically disordered proteins bars intruders from biomolecular condensates
[Slides]
[Video][CC]
2:30pm
Huaiying Zhang (Carnegie)
Nuclear condensate formation and function
[Video][CC]
2:45pm
David Zwicker (MPI-DS)
Continuum models for elastic phenomena inside and outside condensates
[Video][CC]
3:40pm
Afternoon Break & DISCUSSION TIME
5:30pm
CONFERENCE END SHUTTLE TO BWSCI *Also available to SB Airport and SB Airbus, Goleta location. (See Registration Desk BEFORE WEDNESDAY to sign up.)
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