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KITP Program: Multi-Scale Physics of Normal and Diseased Heart: from Ion Channels to Whole Organ
(Mar 30 - Apr 23, 2026)
Coordinators: Hiroshi Ashikaga, Emilia Entcheva, Flavio H. Fenton, Daisuke Sato, and Yohannes Shiferaw
Scientific Advisors: Eberhard Bodenschatz, Alain Karma, Sanjiv Narayan, and M Cristina Marchetti

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Speakers: Please contact us about file upload for your slides.

Time Speaker Title
3/30, 9:30am Daisuke Sato
UC Davis
Welcome[Video]
3/30, 10:15am Yohannes Shiferaw
CSU Northridge
Nonlinear calcium and sodium dynamics underlie arrhythmia initiation at the Purkinje-ventricular junction[Video]
3/31, 9:00am Yixuan Wu
UC Davis
Unveiling Sex-specific Mechanisms of Atrial Ca2+ Dysregulation and Ca2+-driven Arrhythmia via Multiscale Modeling[Embargoed]
4/01, 9:00am Emiliano Medei
UFRJ
Resident macrophages mediate arrhythmia through IL-1b[Video]
4/01, 10:15am Amin Forouzandehmehr
UC Davis
Systems-Level Transcriptomics Reveals Pathway-Selective Translational Alignment Across Murine Models of Cardiometabolic HFpEF[Embargoed]
4/02, 9:00am Enrique Alvarez Lacalle
Barcelona Tech
Are calcium waves always arrhythmogenic? Recent evidence from experiments and nanometric mouse models[Video]
4/02, 10:15am Jeff Saucerman
University of Virginia
Towards Cardiac Inflammation-Fibrosis Coupling[Video]
4/03, 1:00pm Enrique Lacalle
Barcelona Tech
Are calcium waves always arrhythmogenic? Insights from the nanoscale biophysics of RyR2 regulation and Calsequestrin-RyR2 coupling : Part II[Embargoed]
4/03, 9:00am Emilia Entcheva
George Washington
From gene expression to function: high-throughput technologies for manipulating & characterizing human iPSC-cardiomyocytes[Video]
4/06, 9:00am Alain Karma
Northeastern
Calcium-mediated triggered activity: bridging cellular and tissue scales[Video]
4/06, 10:15am Daisuke Sato
UC Davis
The Heart Stirs Before It Breaks: Dynamical Origin of QT Interval Variability[Video]
4/06, 12:15pm Flavio Fenton
Georgia Tech
How your heart works: A Physics Perspective [Video]
KITP Blackboard Lunch
4/07, 9:00am Niels Otani
RIT
The effect of ephaptic coupling on the development of spatially discordant alternans and spiral wave turbulence[Video]
4/07, 10:15am Rengasayee Veeraraghavan
Ohio State
How I learned to stop worrying and love the ephapse[Video]
4/07, 1:00pm Jose Puglisi
CNSU
Feed-Forward Modeling: Fixing the Force-Frequency Relationship[Video]
4/08, 9:00am Emiliano Diez
CONICET
Connexin onset, APD rime fails some times to rhyme but emergent rhythm must follow the algorithm[Video][CC]
4/08, 10:15am Seth Weinberg
Ohio State
Modeling frameworks to investigate ion channel homeostasis and intercellular coupling[Video][CC]
4/09, 9:00am Jeffrey Saucerman
Univ. Virginia
Towards network dynamics of cardiac development: Return of the calcium[Video][CC]
4/09, 10:15am Blas Echebarria
Barcelona Tech
Effects of compartmentation and differential spatial properties in cardiac myocytes[Video][CC]
4/10, 9:00am Yasser Aboelkassem
UM Flint
Stochastic Multiscale Modeling of Cardiac Sarcomere Function Using Langevin Dynamics[Video][CC]
4/10, 10:15am Seth Weinberg
Ohio State
Modeling frameworks to investigate ion channel homeostasis and intercellular coupling Part 2[Video][CC]
4/10, 1:00pm Alessio Gizzi
Bio-Medico Univ.
Gastrointestinal ElectroMechanics: Similarities with the Heart[Video][CC]
4/10, 1:30pm Daisuke Sato
UC Davis
Ablation, Percolation, and Afterdepolarization[Video][CC]
4/13, 10:15am Gil Bub
(McGill Univ.)
Thomas Bury
(McGill Univ.)
Magic patterns[Embargoed]
4/14, 9:00am Tim De Coster
MPI-DS
Gating slope as a control parameter for Canard-mediated EADs and bistability in a reduced excitable system[Video][CC]
4/14, 10:15am Jean Bragard
Univ. Navarra
Fluid-Structure modeling of a contracting atrium[Video][CC]
4/14, 1:00pm Jan Christoph
UCSF
Dreaming of Electrical Waves: Generative Modeling of Cardiac Excitation Waves using Diffusion Models[Video][CC]
4/15, 9:00am Emilia Entcheva
George Washington
Cardiac stimulation by light, ultrasound and magnetic fields directly or through cell spheroids[Embargoed]
4/15, 10:15am Alessandro Veneziani
Emory
Are Mathematicians Critical in the Clinics of Cardiovascular Diseases?[Video]
4/15, 1:00pm All Participants Short talks / discussion session
4/16, 9:00am Carolyn Martsberger
Wofford
Alternate Pacing and Chaos in Paced Cardiac Tissue[Video][CC]
4/16, 10:15am Alessio Gizzi
Bio-Medico Univ.
Open Questions on Cardiac Magnetic Activity and Cardiac Ablation[Video][CC]
4/16, 1:00pm Markus Merk
(UCSB)
Henrik Weyer
(KITP)
Cardiac organoids as active solids[Video][CC]
4/17, 9:00am Tim De Coster
MPI-DS
Which came first, the chicken or the egg? A road towards prevention instead of treatment[Video][CC]
4/17, 10:15am Jan Christoph
UCSF
Bridging the Gap between Imaging and Numerical Modelling of the Heart’s Electromechanics[Embargoed]
4/20, 9:00am Alain Karma
Northeastern
Dynamics of cardiac repolarization in heterogeneous tissue and its role in triggered activity[Video][CC]
4/20, 10:15am Zhilin Qu
UCLA
Cardiac arrhythmogenesis: From bedside to bench and back[Video][CC]
4/21, 9:00am Thomas Bury
McGill Univ.
Predicting bifurcations in cardiac dynamics: from chick heart aggregates to the clinic[Video][CC]
4/21, 10:15am Shahriar Iravanian
Emory
The Hard Problems of Electrophysiolgy: Atrial and Ventricular Fibrillation[Video][CC]
4/21, 1:00pm Abouzar Kaboudian
AKcelerate Computing
Real-Time Computational Research: Applications to the Topics Discussed at KITP[Embargoed]
4/22, 9:00am Evan Rheaume
Georgia Tech
Keela Making Optical Mapping Accessible[Video][CC]
4/22, 9:30am Casey Lee Trimble
Georgia Tech
Optical Mapping During PFA and Induction of Reentry[Video][CC]
4/22, 10:15am Flavio Fenton
Georgia Tech
From Normal Heart Oscillations to Chaos (Arrhythmias) and Back.[Video][CC]
4/22, 1:00pm Stefan Luther
MPI-DS
Low Energy Control of Cardiac Arrhythmias[Video][CC]
4/23, 9:00am Julia Gorelik
Imperial College
Cardiac nanodomains in heart failure[Video][CC]
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